US COVID-19 death toll tops 800,000; but is omicron milder? Get the latest

The U.S. death toll from COVID-19 topped 800,000 on Tuesday, a once-unimaginable figure seen as doubly tragic, given that more than 200,000 of those lives were lost after the vaccine became available practically for the asking last spring.

The number of deaths, as compiled by Johns Hopkins University, is about equal to the population of Atlanta and St. Louis combined, or Minneapolis and Cleveland put together. It is roughly equivalent to how many Americans die each year from heart disease or stroke.

The United States has the highest reported toll of any country. The U.S. accounts for approximately 4% of the world’s population but about 15% of the 5.3 million known deaths from the coronavirus since the outbreak began in China two years ago.

The true death toll in the U.S. and around the world is believed to significantly higher because of cases that were overlooked or concealed.

Latest updates:

The omicron variant is offering more hints about what it may have in store as it spreads around the globe: A highly transmissible virus that may cause less severe disease, and one that can be slowed — but not stopped — by today’s vaccines.

An analysis Tuesday of data from South Africa, where the new variant is driving a surge in infections, suggests the Pfizer vaccine offers less defense against infection from omicron and reduced, but still good, protection from hospitalization.

The findings are preliminary and have not been peer-reviewed — the gold standard in scientific research — but they line up with other early data about omicron’s behavior, including that it seems to be more easily spread from person to person.

Here are other developments today: